Interleukin-2 composition

Details Interleukin-2 composition Interleukin-2 composition

A - Human Necessities

61

K

167/103.2

A61K 38/20 (2006.01)

Patent

CA 1288340

ABSTRACT Stable interleukin-2 (hereinafter abbreviated as IL-2) compositions containing serum albumin and showing pH 6.1 to 9 in 8 state of solution, which are very useful in treatment of various cancers or immunodeficiency diseases. The compositions are prepared by adjusting a solution of interleukin-2 at pH 8-11, more preferably at pH 9-11 with a base and immediately thereafter at pH 6.1-9 with an acid; or by adjusting said solution at pH 2-6, more preferably at pH 214 with an acid and immediately thereafter at pH 6.1-9 with a base.

526570

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