Recombinant retroviruses

Details Recombinant retroviruses Recombinant retroviruses

A - Human Necessities

61

K

167/130, 195/1.2

A61K 35/76 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 15/867 (2006.01)

Patent

CA 1341585

Recombinant retroviruses carrying a vector construct capable of preventing, inhibiting, stabilizing or reversing infectious, cancerous or auto-immune diseases are disclosed. More specifically, the recombinant retroviruses of the present invention are useful for (a) stimulating a specific immune response to an antigen or a pathogenic antigen; (b) inhibiting a function of a pathogenic agent, such as a virus; and (c) inhibiting the interaction of an agent with a host cell receptor. In addition, eucaryotic cells infected with, and pharmaceutical compositions containing such a recombinant retrovirus are disclosed. Various methods for producing recombinant retroviruses having unique characteristics, and methods for producing transgenic packaging animals or insects are also disclosed.

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