Pyridyl and pyrimidyl derivatives

Details Pyridyl and pyrimidyl derivatives Pyridyl and pyrimidyl derivatives

C - Chemistry, Metallurgy

07

D

167/208, 260/246

C07D 401/04 (2006.01) C07D 213/72 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 213/85 (2006.01) C07D 239/42 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 413/14 (2006.01)

Patent

CA 1321997

ABSTRACT The present invention concerns novel compounds of the formula: Image (I) wherein R1 and R2 are the same or different and selected from hydrogen and halogen: R3 and R4 are the same or different and selected from hydrogen and lower alkyl; n is 2 or 3; A is selected from the following pyrimidyl or pyridyl groups Image Image Image Image wherein R5 is selected from hydrogen, lower alkyl or halogen; R6 and R7 are the same or different and selected from hydrogen, halogen, lower alkyl, electron donor groups such as lower alkoxy or hydroxy, electron acceptor groups such as cyano, nitro, trifluoromethyl, COOR8, CONR9 or CO-B; wherein R8 is hydrogen or lower alkyl; R9 and R10 are the same or different and selected from hydrogen, lower alkyl and cycloalkyl; B is selected from Image Image wherein m is 1, 2, 3 or 4. R11 is selected from hydrogen or lower alkyl, and the pharmaco- logically active salts thereof. The new compounds can be used for treating mental disorders.

563050

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