Diamino-androstane derivatives, process for their...

Details Diamino-androstane derivatives, process for their... Diamino-androstane derivatives, process for their...

C - Chemistry, Metallurgy

07

J

260/18, 167/191

C07J 43/00 (2006.01) A61K 31/58 (2006.01) C07J 13/00 (2006.01) C07J 41/00 (2006.01) C07J 71/00 (2006.01)

Patent

CA 1314868

Abstract The invention relates to new 6,16-diamino-androstane derivatives of the formula (I) Image (I) and physiologically acceptable di- and monoquaternary salts thereof of the formulae (Ia) Image (Ia) - 2 - (Ib) Image (Ib) (Ic) Image (Ic) - 3 - and (Id) Image (Id) wherein Y is hydrogen or an OAc group, Ac is an alkylcarbonyl group having from 1 to 4 carbon atoms in the alkyl moiety, A is methylene or a group of the formula Image , in which R1 is alkyl having from 1 to 4 carbon atoms, B is methylene, or a group Image or Image , in which R1 is as defined above and R2 is a -CH2-CH2-COOR1 group, and n is 1 or 2, m is 1, 2 or 3, B1 is a group Image or Image , in which R1 and R2 are as defined above, R3 is alkyl or alkenyl having from 1 to 4 carbon atoms, Z is halogen or sulfonyloxy.

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