Method for promoting nerve regeneration

Details Method for promoting nerve regeneration Method for promoting nerve regeneration

A - Human Necessities

61

K

167/202, 167/218

A61K 47/00 (2006.01) A61K 33/40 (2006.01)

Patent

CA 1254514

Abstract of the Invention A method for promoting regeneration of damaged nerve tissue, comprising administering, either alone or in combination, an effective amount of an antimitotic agent or a proton-withdrawing buffer to the damage site. Antimitotic agents reduce the rate of growth of glial cells, and buffers facilitate the growth of nerve tissue and inhibit glial cell growth. Referred antimitotic agents are cytosine arabinoside, 5-fluorouracil, and hydroxyurea. Preferred buffers are TREA and HEPES. Compositions are disclosed which include antimitotic agent, buffer, and an oxygen-supplying compound, such as hydrogen peroxide.

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