Radioactive chemical product for use as a diagnostic agent

C - Chemistry – Metallurgy – 08 – B

Patent

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260/210, 402/70

C08B 31/00 (2006.01) C08B 33/00 (2006.01) C08B 37/02 (2006.01)

Patent

CA 1258850

- 1 - Abstract: The invention provides a chemical product which comprises (1) a unit of a polyformyl compound having at least three formyl groups per molecule, (2) at least two units of an amino group-containing chelating compound bonded to the polyformyl compound via a methyleneimine linkage (-CH=N-) or a methyleneamine linkage (-CH2NH-) formed by the condensation between a formyl group in the polyformyl compound and the amino group in the chelating compound, optionally followed by reduction, (3) at least one unit of an amino group-containing physiologically active substance bonded to the polyformyl compound via a methyleneimine linkage or a methyleneamine linkage formed by the condensation between a formyl group in the polyformyl compound and the amino group in the physiologically active substance, optionally followed by reduction, and (4) at least two radioactive metallic elements of which each is bonded to the chelating compound through a chelating bond. The product can be used as a diagnostic agent for non-invading nuclear medical diagnosis.

570616

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