Cephalosporin derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 501/18 (2006.01) C07D 501/24 (2006.01)

Patent

CA 1340609

7-[2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(substituted)- iminoacetamido]-3-[3-(quaternaryammonio)-1-propen-1-yl]-3-cephem- 4-carboxylates of the formula Image in which R1 and R2 are as defined herein and -N~Q is a quaternary ammonio group as defined herein, and salts, solvates, hydrates and esters thereof, are potent antibacterial agents. Processes for their preparation and intermediates in such processes are described.

615909

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