Process for the detection of cancer using nuclear magnetic...

Details Process for the detection of cancer using nuclear magnetic... Process for the detection of cancer using nuclear magnetic...

G - Physics

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324/1

G01N 33/49 (2006.01) G01N 24/08 (2006.01) G01N 33/574 (2006.01) G01R 33/465 (2006.01) G01R 33/56 (2006.01)

Patent

CA 1291532

ABSTRACT OF THE DISCLOSURE A technique is disclosed for the detection of cancer using nuclear magnetic resonance (NMR). Specifically, NMR parameters for protons of lipid methyl and/or methylene groups are determined and compared against a corresponding value for healthy patients. In the preferred embodiments, an NMR spectrometer is employed in conjunction with a Fourier transformer to provide a spectrum for non-water components of blood, blood serum or blood plasma and the width of the methyl and/or methylene groups is measured at half- height as a determination of spin-spin relaxation time (T2) which is the parameter used for purposes of comparison with healthy controls. Suppression of the water proton signal is employed where necessary in order to obtain a suitable spectrum for the non-water component protons.

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