Thiobarbituric acid derivatives

Details Thiobarbituric acid derivatives Thiobarbituric acid derivatives

C - Chemistry, Metallurgy

07

D

167/221, 260/256

C07D 401/12 (2006.01) A01N 43/54 (2006.01) A61K 31/515 (2006.01) C07C 65/24 (2006.01) C07D 213/643 (2006.01) C07D 239/66 (2006.01)

Patent

CA 1264746

- 1 - 5-14999/+ Thiobarbituric acid derivatives Abstract of the Disclosure The invention relates to novel 5-phenylcarbamoylthlobarbituric acid derivatives of the general formula Image wherein R1 and R2 are each independently C1-C5alkyl or methoxy, R3 is unsubstituted phenyl, unsubstituted pyridyl, or phenyl which is substituted by 1 to 3 identical or different members selected from the group consisting of C1-C5alkyl, C1-C4cyanoalkyl, halogen, nitro and C1-C5haloalkyl containing 1 to 5 halogen atoms, or is pyridyl which is substituted by 1 to 3 identical or different members selected from the group consisting of C1-C5- alkyl, halogen, nitro and C1-C5haloalkyl containing 1 to 5 halogen atoms and R4 and R5 are each independently hydrogen, halogen, C1-C5alkyl, C1-C2haloalkyl containing 1 to 3 halogen atoms, or are C1-C3- alkoxy or nitro, - 2 - and to the tautomers and salts thereof, as anthelmintics. The compounds may be used by themselves or together with suitable carriers and further adjuvants for controlling helminths which are parasites of animals.

486322

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