Substituted phenylpiperazinyl-propanols, a process for their...

Details Substituted phenylpiperazinyl-propanols, a process for their... Substituted phenylpiperazinyl-propanols, a process for their...

C - Chemistry, Metallurgy

07

D

167/223, 260/266

C07D 401/12 (2006.01) A61K 31/495 (2006.01) C07D 213/85 (2006.01)

Patent

CA 1241959

Abstract Substituted phenylpiperazinyl-propanols of the formula I Image (I) in which R1 denotes hydrogen or an alkyl group with 1 to 4 carbon atoms and R2 and R3, which can be identical or different, each denote hydrogen, halogen, cyano, a tri- fluoromethyl group, a nitro group, a hydroxyl group, an alkoxy group or an alkyl group with in each case 1 to 4 carbon atoms, it being possible for the alkyl parts in each case to be straight-chain or branched, and their tautomeric forms and their salts as well as acid addition salts and N-oxides, have useful pharmacological proper- ties, in particular a positively inotropic, vasodilating, broncholytic and platelet aggregation-inhibiting action and are therefore suitable for the treatment of cardiac insufficiency, hypertension, asthma and thrombosis.

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