Lactone derivative, process for the preparation thereof, and...

C - Chemistry – Metallurgy – 07 – D

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260/233.2, 167/5

C07D 493/22 (2006.01) A01N 43/90 (2006.01) C07H 19/01 (2006.01)

Patent

CA 1242436

A novel lactone derivative, process for the preparation thereof, and use thereof in pest control Abstract of the Disclosure The compound of formula I Image wherein R2 is methyl, ethyl, isopropyl or sec-butyl, can be prepared by selective chlorination of an appropriate milbemycin derivative either with hypochlorous acid (HOCl) or sulfuryl chloride (SO2Cl2) in the temperature range from -10° to +60°C. It is employed as pesticide for controlling Arthropode species such as injurious insects or ecto- or endoparasites of animals, and is applied in the form of compositions. This compound is also used as intermediate for obtaining further milbemycin derivatives.

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