Therapeutic enzymes

A - Human Necessities – 61 – K

Patent

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Details

195/76, 167/103.

A61K 47/48 (2006.01) A61K 39/395 (2006.01) C12N 9/96 (2006.01) C12N 11/02 (2006.01)

Patent

CA 1321750

Abstract of the Disclosure A complex of a therapeutically effective enzyme and a monoclonal antibody specific for the enzyme, the antibody being bound to the enzyme by immunoaffinity, the KD of the antibody/enzyme complex being at least 10- 1 1M, the antibody being bound to the enzyme at a site on the enzyme which does not substantially interfere with the activity of the enzyme and which increases the in vivo half-life of the enzyme.

564004

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