Inductive collagen-based bone repair preparation

Details Inductive collagen-based bone repair preparation Inductive collagen-based bone repair preparation

A - Human Necessities

61

L

167/104, 167/325

A61L 27/00 (2006.01) A61K 35/32 (2006.01) A61L 27/22 (2006.01) A61L 27/46 (2006.01)

Patent

CA 1335177

An improved process for the preparation of mineral/collagen/OF (osteogenic factor) inductive implants for bone repair utilizes drying, under ambient pressure conditions, a suspension of 75-95% mineral particles, 5- 25% collagen, and an effective amount of OF, such as 0.5-4% partially purified OFE or its equivalent wherein the concentration of collagen in the suspension subjected to drying is 30-100 mg/ml. The resulting implants are improved. They are homogeneous in composition and have a high compressive modulus as well as containing OF in a biologically active and available form.

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