Spirothiazolidinyl piperazine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 417/00 (2006.01) C07D 213/85 (2006.01) C07D 277/60 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1208642

SPIROTHIAZOLIDINYL PIPERAZINE DERIVATIVES Abstract of the Disclosure . Piperazinyl derivatives containing a spiro-2,4-thiazoli- dinedione heterocyclic component with relatively selective psychotropic properties are disclosed. The compound 2-[4-[4-(7,9-dioxo-6-thia-8- azaspiro[4.4]nonan-8-yl)butyl]-1-piperazinyl]pyrldine-3-carbonitrile which has selective anti-psychotic activity constitutes a typical embodiment of the invention.

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