Therapeutic methods using catalytic antibodies

Details Therapeutic methods using catalytic antibodies Therapeutic methods using catalytic antibodies

A - Human Necessities

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A61K 39/395 (2006.01) A61K 38/43 (2006.01) A61K 39/00 (2006.01) A61P 31/04 (2006.01) A61P 37/08 (2006.01) C07C 229/46 (2006.01) C07C 229/48 (2006.01) C07C 235/74 (2006.01) C07C 271/24 (2006.01) C07C 311/06 (2006.01) C07C 317/44 (2006.01) C07D 205/085 (2006.01) C07D 207/404 (2006.01) C07F 9/24 (2006.01) C07F 9/30 (2006.01) C07F 9/32 (2006.01) C07F 9/40 (2006.01) C07F 9/553 (2006.01) C07K 16/00 (2006.01) C07K 16/10 (2006.01) C12N 5/12 (2006.01) C12N 9/00 (2006.01) C12P 21/08 (2006.01) C12Q 1/25 (2006.01) G01N

Patent

CA 1341478

Antigens capable of eliciting antibodies which can catalyze chemical reactions, in particular, the cleavage or formation of a peptide linkage, comprising a hapten or a hapten and a suitable carrier molecule are disclosed. Haptens include, among others, silicon and boron containing compounds. antibodies which are catalytically active for chemical reactions, in particular, the cleavage or formation of an amide, peptide, ester, or glycosidic bond, and which are elicited by such antigens are disclosed as well as methods for producing the antibodies, methods for catalyzing the cleavage or formation of an amide, peptide, ester, or glycosidic bond in a biomolecule, and methods for treating a variety of diseases using antibodies.

598697

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