Disubstituted pyridines

Details Disubstituted pyridines Disubstituted pyridines

C - Chemistry, Metallurgy

07

D

167/211, 260/242

C07D 213/55 (2006.01) A61K 31/44 (2006.01) C07D 213/80 (2006.01) C07D 213/82 (2006.01) C07D 213/85 (2006.01) C07D 213/89 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/02 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 409/04 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1340798

New substituted pyridines can be prepared by reduction of pyridines which are substituted by a ketone radical, and subsequent hydrolysis, cyclization or hydrogenation. The new compounds can be used as active compounds in medicaments, particularly for inhibiting HMG-CoA reductase, for inhibiting cholesterol biosynthesis or for the treatment of hyperlipoproteinaemia, lipoproteinaemia or arteriosclerosis.

588502

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