Supression of cell proliferation by decorin

Details Supression of cell proliferation by decorin Supression of cell proliferation by decorin

C - Chemistry, Metallurgy

07

K

530/13, 195/1.34

C07K 14/78 (2006.01) A61K 38/39 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1340112

The present invention relates to the proteoglycan Decorin (also known as PG-II or PG-40). The invention provides cells transfected with and expressing a gene coding for Decorin. Spent culture media from such transfected cell cultures can be used to suppress the proliferation of either normal or abnormal cells. Purified Decorin can be used to suppress cell proliferation.

604090

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