Pharmaceutical compositions

A - Human Necessities – 61 – K

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A61K 31/395 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 47/02 (2006.01)

Patent

CA 1215647

ABSTRACT Pharmaceutical Compositions A solid pharmaceutical composition comprising one or more .beta.-lactam antibiotics in acid or amphoteric form in association with at least one physiologically acceptable base in the presence of a gaseous atmosphere containing a stabilising amount of carbon dioxide at a concentration greater than that of atmospheric air. The compositions exhibit enhanced stability. A preferred antibiotic for the compositions is ceftazidime or a hydrate thereof, and a preferred base is sodium carbonate or a mixture thereof with one or more other bases.

436412

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