Substituted alkanoylimidazol-2-one derivatives

Details Substituted alkanoylimidazol-2-one derivatives Substituted alkanoylimidazol-2-one derivatives

C - Chemistry, Metallurgy

07

D

260/280, 260/305

C07D 233/70 (2006.01) C07D 233/84 (2006.01) C07D 405/06 (2006.01)

Patent

CA 1227487

NOVEL SUBSTITUTED ALKANOYLIMIDAZOL- 2-ONE DERIVATIVES ABSTRACT OF THE DISCLOSURE Novel 4-alkanoylimidazol-2-ones of the following general structure which are useful as cardiotonics in the treatment of cardiac failure Image wherein Q and T are each an oxygen atom or a divalent sul- fur atom; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; R1 is hydrogen or lower alkyl; R2 is a lower aliphatic hydrocarbon radical, phenyl alkylene or hetero- cyclo alkylene; and the pharmaceutically acceptable salts thereof.

414707

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