Substituted pyrrolo[2,1-b]quinazolines and...

Details Substituted pyrrolo[2,1-b]quinazolines and... Substituted pyrrolo[2,1-b]quinazolines and...

C - Chemistry, Metallurgy

07

D

260/242.01

C07D 471/04 (2006.01) C07D 487/04 (2006.01)

Patent

CA 1183135

Abstract of the Disclosure The invention provides novel substituted pyrrolo[2,1-b] and pyrido[2,1-b]quinazolines of formula I Image (I) or a pharmaceutically acceptable salt thereof, wherein n is 1 or 2; each of R and R1 independently represents: a) a hydrogen or a halogen atom; b) a C1-C4 alkyl group, a - CH2OH group or a cyano group; c) a carboxy group or a group - COOR6, wherein R6 represents a C1-C6 alkyl group which may be un- substituted or substituted by C1-C4 dialkylamino group; d) a group - Image wherein each of R7 and R8 independently represents a hydrogen atom or a C1-C4 alkyl group; e) amino, a C2-C6 alkanoylamino group or a formylamino group, at least one of R and R1 being different from hydrogen when n is 1; R2 represents a hydrogen atom or a C1-C4 alkyl group; each of R3, R4 and R5 independently represents a hydrogen or a halogen atom, a hydroxy group, formyloxy, a C2-C8 alkanoyloxy group, a -CF3 group, a C1-C4 alkyl group, a C1-C4 alkoxy group or a C3-C4 alkenyloxy group or adjacent groups represented by two of R3, R4 and R5, taken together, form a C1-C3 alkylenedioxy group. The compounds are active on the gastroenteric system and in particular they display anti-ulcerogenic and anti-secretory activity.

406308

Affiliated with

Also associated with

Rating

Substituted pyrrolo[2,1-b]quinazolines and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted pyrrolo[2,1-b]quinazolines and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted pyrrolo[2,1-b]quinazolines and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1330878