Process for the preparation of anti-inflammatory...

A - Human Necessities – 61 – K

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167/158, 167/262

A61K 31/19 (2006.01) A61K 9/46 (2006.01)

Patent

CA 1336323

Disclosed in an anti-inflammatory pharmaceutical composition comprising the following ingredients in intimate admixture: ibuprofen, 200 to 800 mg or ibuprofen sodium salt, 221.2 to 885.2 mg; sodium bicarbonate, 2.100 to 8.402 g; and citric acid, 0.450 to 1.800 g. This composition which can be in the form of an effervescent solution or a tablet, permits to eliminate the bitter taste, the burning of the throat and the topical toxicity at the level of the intestinal wall, that are otherwise encountered with similar compositions.

605401

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