Process for producing proteins correlated with the...

Details Process for producing proteins correlated with the... Process for producing proteins correlated with the...

C - Chemistry, Metallurgy

12

P

195/1.31

C12P 21/00 (2006.01) A61K 39/05 (2006.01) C07K 14/34 (2006.01)

Patent

CA 1212642

PROCESS FOR PRODUCING PROTEINS CORRELATED WITH THE DIPHTHERIC TOXIN ABSTRACT Process for the production of a protein correlated with the diphtheric toxin which comprises culturing in a liquid nutrient medium having a concentration of iron ions of from 0.05 µg/ml to 0.5 µg/ml, at a temperature of from 30°C to 40°C, in a neutral culturing environ- ment and under aerobic conditions, a microorganism belonging to the Corynebacterium diphtheriae genus with two mutant phages encoding the protein correlated with the diphtheric toxin integrated in a nontandem mode in their chromosomes.

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