Rapid differentiation of fungi from bacteria using polyene...

C - Chemistry – Metallurgy – 12 – Q

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150/1, 150/16.1

C12Q 1/04 (2006.01) G01N 33/52 (2006.01)

Patent

CA 1290226

RAPID DIFFERENTIATION OF FUNGI FROM BACTERIA USING POLYENE ANTIBIOTICS Abstract of the Disclosure Rapid differentiation between viable fungi (for example, yeast) and viable bacteria is accomp- lished with certain polyene antibiotics which are used in combination with a compound which is normally reducible by both the fungi and the bacteria. The antibiotics selectively and substantially inhibit the reduction of the reducible compound by the fungi but do not affect the reducing capacity of the bacteria. The particular antibiotics useful are polyenes which selectively affect the function of the cytoplasmic membrane of fungi.

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