G - Physics – 01 – N
Patent
G - Physics
01
N
150/11
G01N 33/48 (2006.01) G01N 33/96 (2006.01)
Patent
CA 1249208
ABSTRACT This invention primarily is directed to a hematology reference control solution, the three separate white cell control portions thereof consisting of three types of fixed red cells of determined size distribution for checking the operation of a particle analyzing instrument, including its predetermined lower and upper threshold settings for each class or subclass of leukocytes. For preparing a human granulocyte analogue, nurse shark erythrocytes are altered and fixed in a chilled solution to simulate in number, size and distribution the granulocytes in human whole blood. Such a granulocyte analogue is useful as a free-standing reference control, for determination of human granulocytes only, or can be comingled with reference controls for lymphocytes and mononuclear cells for use with multi-parameter instruments to give a trimodal leukocyte reference control, which itself can be included in a multiple-analysis hematology reference control, having components for also determining red blood cell and platelet parameters.
481779
Carver Franklin J.
Gerula Theodore J.
Borden Ladner Gervais Llp
Coulter International Corp.
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