Sulfoxide derivatives and their preparation

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/44 (2006.01) C07D 241/44 (2006.01) C07D 401/12 (2006.01)

Patent

CA 1304087

NOVEL SULFOXIDE DERIVATIVES AND THEIR PREPARATION ABSTRACT OF THE DISCLOSURE Novel sulfoxide derivatives showing a gastric acid- secretion inhibitory effect which have the formula (I): (I) Image wherein each of R1 and R2 independently is hydrogen or a lower alkyl group, and each of R3, R4, R4a and R4b independently is hydrogen, halogen, a lower alkoxy group, a lower alkyl group, trifluoromethyl, or a fluorine atom- containing lower alkoxy group. Other novel sulfoxide derivatives are also disclosed.

527149

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