Formulations for inhibiting glucose transport

A - Human Necessities – 61 – K

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167/199, 167/280

A61K 31/70 (2006.01) A61K 31/12 (2006.01) A61K 47/20 (2006.01)

Patent

CA 1319107

ABSTRACT A formulation suitable for use for treating cancer, the formulation comprising: (a) a glucose inhibiting (non-toxic) amount of an agent that blocks the glucose transport protein (active transport molecule in the membrane) of a cell from transporting glucose into the cell, and (b) an effective (non-toxic) amount of an agent which (i) enhances penetration and transport of agent (a) through the tissue surrounding the various cellular elements, generally known as scar tissue or fibrous reaction around the cancerous tumor, and (ii) alters the penetration characteristics of the tissue surrounding the tumor to permit agent (a) to be transported to the center of the tumor.

568512

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