Acrylamidobenzoic acid derivatives and their use

Details Acrylamidobenzoic acid derivatives and their use Acrylamidobenzoic acid derivatives and their use

C - Chemistry, Metallurgy

07

D

167/207, 260/314

C07D 207/337 (2006.01) C07D 207/327 (2006.01) C07D 233/54 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1242731

- 1 - Abstract The invention provide compounds of the general formula: Image (?) wherein R1 is a heterocyclic group other than pyridyl and which is unsubstituted or substituted with a lower alkyl group or a lower alkoxycarbonyl group, R2 is hydrogen, halogen, or nitro, and R3 is a carboxy group or its functional derivative, with the proviso that when R1 is an unsubstituted furyl, or furyl mono- or polysubstituted with alkyl and R2 is hydrogen, then R3 is functional derivative of carboxy; and, where applicable, pharma- ceutically acceptable salts thereof. These compounds are hyaluronidase inhibitors and are useful as anti- allergic agents.

475112

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