Primary and secondary alcohol dehydrogenase enzymes and use...

Details Primary and secondary alcohol dehydrogenase enzymes and use... Primary and secondary alcohol dehydrogenase enzymes and use...

C - Chemistry, Metallurgy

12

N

195/129, 195/131

C12N 9/04 (2006.01) C12P 7/00 (2006.01) C12P 7/24 (2006.01) C12P 7/26 (2006.01)

Patent

CA 1211728

ABSTRACT OF THE DISCLOSURE A newly discovered and isolated heat-stable NAD (P)+-1 inked secondary alcohol-specific dehydrogenase enzyme is derived from microorganisms grown under aerobic conditions in a culture medium containing a carbon-containing compound having at least two carbon atoms, preferably a C2-C10 alkane or a C2-C10 alkyl radical donating compound, as the major carbon and energy source. The purified form of this enzyme, in the presence of NAD(P)+, is capable of converting primary and secondary alcohols, diols and aldehydes to their corresponding oxidation products and acetone to propanol. In addition, a newly discovered NAD(P)+-linked primary alcohol dehydrogenase enzyme can be isolated from the same microorganism source.

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