Cephalosporin compounds, processes for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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260/290.3, 260/2

C07D 213/89 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1333713

The present invention provides a compound having the formula Image (II) wherein R2 is a hydrogen atom or an amino-protecting group selected from a tri-alkylsilyl group, an acyl group, a chloroacetyl group, a p-methoxybenzyloxycarbonyl group, a t- butoxycarbonyl group, a 2,2,2-trichloroethoxycarbonyl group, a p- nitrobenzyloxycarbonyl group, an aralkyl group, a p-methoxybenzyl group, a p-nitrobenzyl group, a benzhydryl group and a trityl group, and each of R3 and R4 is a hydrogen atom or a hydroxyl- protecting group, trialkylsily group, a benzhydryl group, a .beta. - methylsulfonylethyl group, a phenacyl group, a p-methoxybenzyl group, a t-butyl group, a p-nitrobenzyl group, and a 2,2,2- trichloroethyl group or a reactive derivative thereof selected from a salt, halide, ester, anhydride, amide, azide which compounds are intermediates in the preparation of cephalosporin antibacterial compounds.

615847

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