Transdermal delivery device having a rate controlling adhesive

A - Human Necessities – 61 – L

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128/104

A61L 15/58 (2006.01) A61F 13/00 (2006.01) A61K 9/70 (2006.01) A61M 37/00 (2006.01)

Patent

CA 1297754

ARC 1316 ABSTRACT OF THE DISCLOSURE A transdermal delivery device having a release-rate controlling- adhesive is disclosed having improved delivery characteristics. The device employs a polyisobutylene/mineral oil adhesive formulation and an ethylene/vinyl acetate (EVA) drug reservoir formulation. The device is useful in delivering a wide variety of transdermally administrable drugs, particularly those which are moderately soluble in mineral oil. Preferred embodiments deliver timolol base and atropine base from an EVA (40% VA) reservoir formulation.

545836

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