Method for restoring depleted purine nucleotide pools

Details Method for restoring depleted purine nucleotide pools Method for restoring depleted purine nucleotide pools

A - Human Necessities

61

K

167/202

A61K 31/70 (2006.01) A61K 31/415 (2006.01) C07H 19/052 (2006.01)

Patent

CA 1229303

-42- A Method For Restoring Depleted Purine Nucleotide Pools Abstract A method of increasing the rate of repletion of purine nucleotide pools in tissue deficient in the nucleotides, which comprises administering to a human or animal a therapeutically effective amount of 5- amino-4-imidazolecarboxamide riboside, 5-amino-4- imidazolecarboxamide, or a pharmaceutically acceptable salt thereof sufficient to increase the rate of the repletion is disclosed along with pharmaceutical compositions useful for carrying out the method of the invention.

453519

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