Ethers

C - Chemistry – Metallurgy – 07 – D

Patent

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167/211, 260/261

C07D 451/06 (2006.01) A61K 31/395 (2006.01) C07D 453/02 (2006.01)

Patent

CA 1307790

AHP-386/395 ABSTRACT ETHERS Novel ethers of formula Image (I) their heteroaromatic N-oxides, and the pharmaceutically acceptable acid additions of the compounds of formula (I) and their N-oxides possess 5-HT3-antagonistic activity. In the formula Image represents an optionally substituted heteroaryl group containing a hetero atom X and -B represents a saturated azabicyclic ring such as quinuclidyl or tropanyl.

573471

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