Method of manufacturing pharmaceutical articles

Details Method of manufacturing pharmaceutical articles Method of manufacturing pharmaceutical articles

B - Operations, Transporting

65

D

B65D 41/58 (2006.01) A61J 1/00 (2006.01) B29C 35/16 (2006.01) B29C 37/00 (2006.01) B29C 45/00 (2006.01) B29C 45/14 (2006.01) B29C 45/16 (2006.01) B29C 71/00 (2006.01) B65D 41/50 (2006.01) B65D 51/00 (2006.01)

Patent

CA 2279634

The invention relates to a process of preparing pharmaceutical closures for containers made of flexible polymeric materials which are suitable to be filled with parenterally administerable fluids prior to their sealing and sterilization. The process involves a specific relaxation period for the elastomer material of the closure which thereby can settle and develop resealing characteristics. The closures will have an excellent resealing capacity after being penetrated by a piercing device for establishing fluid communication with the container, even after multiple entries into the container.

L'invention concerne un procédé de préparation de fermetures pharmaceutiques de contenant réalisés dans des matières polymères flexibles et destinés à recevoir des fluides d'administration parentérale avant leur fermeture hermétique et stérilisation. Le procédé comprend une période de relaxation spécifique pour la matière élastomère de la fermeture qui ainsi peut acquérir et développer des caractéristiques lui permettant de se refermer hermétiquement. Ces fermetures présentent ainsi une excellente aptitude à se refermer hermétiquement après avoir été transpercées par un dispositif de perçage permettant d'établir la communication du fluide avec le contenant, et ce même après de multiples pénétrations dans le contenant.

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