Pyrrolotriazinone derivatives for use as stearoyl coa...

Details Pyrrolotriazinone derivatives for use as stearoyl coa... Pyrrolotriazinone derivatives for use as stearoyl coa...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/53 (2006.01) A61P 3/00 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2719362

The present invention discloses pyrrolotriazinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I: The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.

Cette invention concerne des dérivés de pyrrolotriazinone pouvant être utilisés à titre d'inhibiteurs de stéaroyl-CoA désaturase ayant la structure de Formule I : Lesdits composés sont utiles pour traiter et/ou prévenir diverses maladies humaines, médiées par les enzymes stéaroyl-CoA désaturase (SCD), notamment, les maladies liées à des taux lipidiques anormaux, les maladies cardiovasculaires, le diabète, l'obésité, le syndrome métabolique et autres syndromes similaires.

Affiliated with

Also associated with

Rating

Pyrrolotriazinone derivatives for use as stearoyl coa... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrrolotriazinone derivatives for use as stearoyl coa..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolotriazinone derivatives for use as stearoyl coa... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1342039