Treatment of periodontal disease with alendronate

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01)

Patent

CA 2122498

2122498 9311774 PCTABS00022 This invention claims a method for treating periodontal disease in mammals, including humans, by administering an effective amount of 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or a pharmaceutically acceptable salt including the monosodium salt tridydrate (alendronate) of formula (I). The compounds are useful in the treatment of alveolar bone loss associated with periodontitis and periodontal disease.

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