Medicaments

Details Medicaments Medicaments

A - Human Necessities

61

K

167/231

A61K 31/00 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2004301

ABSTRACT The use of a compound of formula (I) or a physiologically acceptable salt or hydrate thereof in the treatment, relief or prevention of the effects of cerebral ischaemia Image (I) Compounds of formula (I) are described in UK Published Patent Application No. 2157691A The compounds of formula (I) have been found to protect mammals, including man, against neuronal damage resulting from cerebral ischaemia. The preferred compound for use in this indication is (?)-trans-5- fluoro-2,3,3a,9a-tetrahydro-1H-[1,4]-benzodioxino[2,3-c]- pyrrole (formula (I), R = H, R1 = F, R2 - H), especially in the form of its hydrochloride salt.

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