Promoters exhibiting endothelial cell specificity and...

A - Human Necessities – 61 – K

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Details

A61K 48/00 (2006.01) A61K 31/198 (2006.01) A61K 31/573 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2638829

Isolated polynucleotide sequences exhibiting endothelial cell specific promoter activity, novel cis regulatory elements and methods of use thereof enabling treatment of diseases characterized by aberrant neovascularization or cell growth are disclosed.

L'inventionn concerne des séquences isolées de polynucléotides présentant une activité de promoteur spécifique de cellules endothéliales, de nouveaux éléments cis régulateurs et leurs méthodes d'utilisation pour permettre de traiter des maladies caractérisées par une néovascularisation ou une augmentation cellulaire aberrante.

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