A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/66 (2006.01) A61K 33/06 (2006.01) A61K 33/42 (2006.01)
Patent
CA 2434544
Glycerophosphates, particularly calcium glycerophosphate (CGP), have been found to mitigate certain abdominal-area physical problems including irritable bowel syndrome and urinary urgency. It is believed that calcium and glycerophosphate, taken orally, are introduced into the human and other animal system such that the glycerophosphate and/or calcium exert a damping, soothing, irritant-interdictive or antispasmodic action on the intestinal, urinary bladder and other smooth muscle organs. Using glycerophosphates, a method is provided for alleviating, palliating, and reducing the syndromes and conditions of discomfort resulting from a variety of diseases, including irritable bowel syndrome, interstitial cystitis, inflammatory bowel disease, fibromyalgia, urinary urgency, benign prostatic hypertrophy, vulvodynia and external genital pain. It is also suggested that muscular energy supplied via glycolysis, the source of anaerobic energy, may be facilitated by the administration of a glycerophosphate moiety to the body's glycerophosphate shuttle.
L'invention concerne des glycérophosphates, notamment des glycérophosphates de calcium (CGP), qui ont révélé atténuer certains problèmes physiques de la zone abdominale, dont le syndrome du côlon irritable et la miction impérieuse. Le calcium et le glycérophosphate, en prise orale, sont introduits dans le système humain ou animal, de façon que le glycérophosphate et/ou le calcium exercent une action d'amortissement, de soulagement, anti-irritante ou antispasmodique sur les intestins, la vessie urinaire et d'autres organes à muscles lisses. L'invention concerne également un procédé utilisant des glycérophosphates dans le but de soulager, de pallier et de réduire les syndromes et les conditions d'inconfort provenant de diverses maladies, dont le syndrome du côlon irritable, la cystite interstitielle, la maladie intestinale inflammatoire, la fibromyalgie, la miction impérieuse, l'hypertrophie prostatique bénigne, la vulvodynie et la douleur génitale externe. L'énergie musculaire fournie via la glycolyse, source d'énergie anaérobie, peut en outre être facilitée par l'administration d'une fraction glycérophosphate à la navette du glycérophosphate du corps.
Finnegan Sarah
Kligerman Alan E.
Akpharma Inc.
Gowling Lafleur Henderson Llp
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