Trifluoromethyl 1-carba(1-dethia)cephems

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 463/00 (2006.01) A61K 31/44 (2006.01) A61K 31/695 (2006.01) C07F 7/10 (2006.01) C07F 7/22 (2006.01)

Patent

CA 2058699

X-8112 ABSTRACT OF THE INVENTION 7-.beta.-Acylamino-1-carba-(1-dethia)-3-trifluoro- methyl-3-cephem-4-carboxylic acids and derivatives are provided as antibiotics. Pharmaceutical formulations comprising the antibiotics, intermediates, and a process for their preparation are also provided.

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