G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 15/10 (2006.01) C12M 1/34 (2006.01) G01N 15/14 (2006.01) G01N 33/483 (2006.01)
Patent
CA 2707015
The present invention provides for a rapid computational method (mtPatterns) to simulate the scattering patterns of biological cells, comprised of an algorithmic method that considers the scattering contributions of a three-dimensional array of scatterers and uses this information to formulate detailed large-angle two- dimensional scattering plots. This method can readily generate scatter pattern simulations that are consistent with those found in published experimental and theoretical results, can and facilitate the identification of experimental scattering images via pattern comparison. Also provided for is a multi-agent system to parameterize laser scattering images of the kind produced by a wide-angle 2D cytometer comprising a three stage pipeline of. feature detection, feature clustering, and post-processing to create a parametric representation of an input scattering image.
L'invention concerne un procédé de calcul rapide (mtPatterns) pour simuler les motifs de dispersion de cellules biologiques, comprenant un procédé algorithmique qui examine les contributions de dispersion d'un réseau tridimensionnel de disperseurs et utilise ces informations pour formuler le tracé de dispersion bidimensionnel grand angle. Ce procédé peut rapidement produire des simulations de motifs de dispersion conformes à celles des résultats expérimentaux et théoriques publiés. Ledit procédé peut également faciliter l'identification d'images de dispersion expérimentales par comparaison de motifs. L'invention concerne en outre un système multi-agent pour paramétrer des images de dispersion laser du type produit par un cytomètre bidiemsionnel grand angle comprenant un pipeline à trois étages, soit: détection de caractéristiques, grappe de caractéristiques, et post-traitement pour créer une réprésentation paramétrique d'une image de dispersion entrée.
Backhouse Christopher
Pilarski Patrick
Su Xuantao
Backhouse Christopher
Pilarski Patrick
Sherburne Craig K.
Su Xuantao
The Governors Of The University Of Alberta
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