Intermediates and methods useful in the semisynthesis of...

C - Chemistry – Metallurgy – 07 – D

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C07D 305/14 (2006.01)

Patent

CA 2479828

The semisynthesis of paclitaxel and its analogs uses new intermediates which are derivatives of 10-deacetyl-baccatin III, the invention also provides methods of preparing these derivatives. These novel derivatives have alkyl carbonate or alkyl carbonyl substituents in the 7 position.

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