C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01)
Patent
CA 2402374
The present invention is concerned with a novel process for the preparation of compounds of formula (I) comprising bromomethylation or chloromethylation of a compound of formula (II) and subsequent reaction with a compound of formula (III). The compounds of formula (I) and the corresponding salts, e.g. the sodium salts, are pharmaceutically active substances.
La présente invention concerne un nouveau procédé de préparation de composés de la formule (I), qui consiste en une bromométhylation ou une chlorométhylation d'un composé de la formule (II) et en la réaction subséquente avec un composé de formule (III). Les composés de la formule (I) et les sels correspondants, à savoir les sels de sodium, sont des substances pharmaceutiquement actives.
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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