Use of leptin for the prevention of excess body weight and...

Details Use of leptin for the prevention of excess body weight and... Use of leptin for the prevention of excess body weight and...

A - Human Necessities

61

K

A61K 38/22 (2006.01) A23L 1/29 (2006.01) A61P 3/06 (2006.01) C07K 14/575 (2006.01)

Patent

CA 2598924

The invention relates to the use of leptin in the preparation of an ingestible composition for children from nursing infants to adolescents, comprising leptin at a concentration greater than 50 ng/kg, for the prevention of excess weight and/or the complications associated therewith. The invention comprises the use of a fully-or partially-hydrolysed recombinant leptin. Said ingestible composition is a supplement for developmental nutrition, contains between 0.1 and 30 micrograms/litre leptin, provides a daily dose of leptin of more than 25 ng and can take the form of a solid, i.e. a tablet, capsule or reconstitutable powder, or a liquid, i.e. a syrup or drink.

L'invention concerne l'utilisation de la leptine dans la préparation d'une composition destinée à être ingérée par des nourrissons et des enfants jusqu'à l'adolescence, contenant de la leptine dans une proportion supérieure à 50 ng/kg, et destinée à prévenir une surcharge pondérale et/ou ses complications. On utilise une leptine de recombinaison entière ou partiellement hydrolysée. Ladite composition est un supplément diététique pour les enfants, avec une concentration de leptine variant de 0,1 à 30 microgrammes/litre, elle apporte une dose de leptine supérieure à 25 ng/jour, et peut être solide, sous forme de tablette, de capsule ou de poudre reconstituée, ou liquide, sous forme de sirop ou de boisson.

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