C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
167/325, 167/327
C12N 11/00 (2006.01) A61L 25/00 (1990.01)
Patent
CA 2011220
BIOLOGICALLY ACTIVE MATERIAL, METHOD FOR PREPARING SAME, AND DRESSING MEANS ABSTRACT OF THE DISCLOSURE A biologically active material comprises, as a carrier, a textile maternal, and an enzyme, immobilized on said tarrier and covalently bound thereto, said components being present in the following weight ratios, per cent by weight: enzyme - 0.02 to 0.50, carrier - 99.98 to 99.50. A method for preparing said material resides in activating said textile material until the formation therein of reactive functional groups in an amount of from 0.0625 to 3.125 mg-equiv. per gram of the carrier, immobilizing on said carrier an enzyme taken from a buffer solution having a pH of from 6.5 to 7.5 at room temperature for 8 to 16 hours to form a covalent chemical bond between said textile material and enzyme, squeezing-out the material thus- obtained, followed by washing the material, drying it, shaping it into medicinal forms, placing it into a container, sealing it off, and sterilizing An individual dressing means is made in the form of a bandage consisting of , arranged in succession therein, a protective layer, an absorbing layer, and a wound- adjoining layer. At least one of said layers is made of said biologically active material.
Filatov Vladimir N.
Ryltsev Vladimir V.
Vlasov Lev G.
Filatov Vladimir N.
Moskovsky Meditsinsky Stomatologichesky Institut Imeni N.a. Sema
Ryltsev Vladimir V.
Swabey Ogilvy Renault
Vlasov Lev G.
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