A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 8/64 (2006.01) A61K 8/66 (2006.01) A61K 38/47 (2006.01) A61Q 11/00 (2006.01)
Patent
CA 2306459
A composition for controlling bacterial growth/colonization is provided. The composition comprises an enzyme, an anchor molecule coupled to the enzyme to form an enzyme-anchor complex, with the anchor being capable of attaching to a substrate proximal to a bacterial colony. The attachment to the substrate permits prolonged retention time of the enzyme-anchor complex where the bacterial colony is present to increase the effectiveness of the complex. The invention is also for a method of controlling colonization of bacterial plaque in the oral cavity, as well as a method of forming a composition for controlling the proliferation of bacterial colonies in the oral cavity.
L'invention concerne une composition destinée à réguler la croissance/la colonisation bactérienne. Cette composition renferme une enzyme et une molécule d'ancrage couplée à cette enzyme de manière à former un complexe enzyme-molécule d'ancrage, cette molécule d'ancrage étant par ailleurs capable de se fixer à un substrat proche d'une colonie bactérienne. Cette fixation au substrat permet d'obtenir un temps de rétention prolongé dudit complexe enzyme-molécule d'ancrage, la présence de la colonie bactérienne étant destinée à améliorer l'efficacité de ce complexe. L'invention concerne également un procédé de régulation de la colonisation d'une plaque bactérienne dans la cavité buccale, ainsi qu'un procédé de formation d'une composition permettant de réguler la prolifération de colonies bactériennes dans la cavité buccale.
Marks & Clerk
Pharmacal Biotechnologies Inc.
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