A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01)
Patent
CA 2298442
The inventive transdermal therapy system (TTS) for releasing an active agent into a human or an animal organism through the skin comprises a matrix (5) containing the active agent, with an adhesive active layer (2) which faces towards the skin and which can be covered with a detachable protective layer (11) before application, and a cover layer (1). Said cover layer (1) is impenetrable to the active agent and forms a barrier between the matrix (5) and the outside. The inventive system is characterised in that at the time of application, a part-section (6) of the surface of the active layer (2) of the matrix (5) which releases the active agent and faces towards the skin is covered by a barrier layer (3), said barrier layer being impenetrable to the active agent.
L'invention concerne un système thérapeutique transdermique (TTS) permettant d'introduire un principe actif dans un organisme humain ou animal par la peau. Ce système comprend une matrice (5) contenant le principe actif et dotée d'une couche active (2) pouvant être recouverte, avant son application, d'une couche de protection (11) détachable et adhésive orientée vers la peau. Ce système comprend également une couche de revêtement (1) imperméable au principe actif et délimitant la matrice (5) vers l'extérieur. Ce système est caractérisé en ce que la couche active (2) de la matrice (5) est recouverte, au moment de l'application et dans une zone partielle (6) de sa surface de libération du principe actif, qui est tournée vers la peau, d'une couche d'arrêt (3) imperméable au principe actif.
Lts Lohmann Therapie-Systeme Ag
Mccarthy Tetrault Llp
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