Conjugated anti-psma antibodies

Details Conjugated anti-psma antibodies Conjugated anti-psma antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61K 39/44 (2006.01)

Patent

CA 2603847

The described invention encompasses novel compositions, methods of treating cancer, methods of diagnosing cancer, pharmaceutical compositions, and methods for making conjugated antibodies which comprise an antibody which immunospecifically binds to prostate specific membrane antigen and is conjugated to a radioisotope via a MeO-DOTA linkage.

L'invention concerne de nouvelles compositions, des méthodes de traitement du cancer, des méthodes de diagnostic du cancer, des compositions pharmaceutiques et des méthodes pour fabriquer des anticorps conjugués comprenant un anticorps qui se lie immunospécifiquement à l'antigène de la membrane spécifique à la prostate et est conjugué à un radio-isotope par une liaison MeO-DOTA.

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