Methods and compositions for treating cancer

Details Methods and compositions for treating cancer Methods and compositions for treating cancer

A - Human Necessities

61

K

A61K 31/58 (2006.01) A61K 31/573 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2661422

Methods and compositions for treating cancer are described herein. More particularly, the methods for treating cancer comprise administering a 17.alpha.-hydroxylase/C17, 20-lyase inhibitor, such as abiraterone acetate (i.e., 3.beta.-acetoxy-17-(3-pyridyl) androsta-5, 16-diene), in combination with at least one additional therapeutic agent such as an anti¬ cancer agent or a steroid. Furthermore, disclosed are compositions comprising a 17.alpha.- hydroxylase/C17, 20-lyase inhibitor, and at least one additional therapeutic agent, such as an anti-cancer agent or a steroid.

L'invention concerne des procédés et compositions servant à traiter un cancer. Plus précisément, les procédés servant à traiter un cancer consistent à administrer un inhibiteur de 17.alpha.-hydroxylase/C17,20-lyase tel que l'acétate d'abiratérone (c'est-à-dire le 3.beta.-acétoxy-17-(3-pyridyl)androsta-5,16-diène), en association avec au moins un agent thérapeutique supplémentaire tel qu'un agent anticancéreux ou un stéroïde. En outre, l'invention concerne des compositions comprenant un inhibiteur de 17.alpha.-hydroxylase/C17,20-lyase et au moins un agent thérapeutique supplémentaire tel qu'un agent anticancéreux ou un stéroïde.

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