C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2560937
Compositions and methods are provided for inducing anti-tumor immunity. More specifically, tumor cells and recombinant constructs are provided that express a cell surface CD83 polypeptide and/or a cell surface expressed antibody that specifically binds to an immune cell receptor, particularly an antibody that specifically binds to CD137. The invention also provides recombinant expression constructs comprising polynucleotides that encode a cell surface CD83 polypeptide, a cell surface expressed anti-immune cell receptor antibody, and/or at least one tumor antigen, and the related expressed products.
La présente invention concerne des compositions et des techniques induisant une immunité antitumorale. Plus spécifiquement, la présente invention concerne des cellules tumorales et des construits de recombinaison qui expriment un polypeptide CD83 de surface cellulaire et/ou un anticorps exprimé de surface cellulaire qui se lie spécifiquement à un récepteur de cellules immunes, en particulier un anticorps qui se lit spécifiquement à CD137. Cette invention concerne aussi des construits d'expression de recombinaison comprenant des polynucléotides codant pour un polypeptide CD83 de surface cellulaire, un anticorps de récepteur de cellules anti immune exprimé de surface cellulaire et/ou au moins un antigène tumoral et, les produits exprimés associés.
Hellstrom Ingegerd
Hellstrom Karl Erik
Yang Yi
Bennett Jones Llp
Washington Research Foundation
Yang Yi
LandOfFree
Compositions and methods for inducing anti-tumor immunity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods for inducing anti-tumor immunity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods for inducing anti-tumor immunity will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1354594