Polyene carboxylic acid derivatives, method for their...

C - Chemistry – Metallurgy – 07 – C

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C07C 57/48 (2006.01) C07C 57/42 (2006.01) C07C 59/48 (2006.01) C12P 7/42 (2006.01) C12P 7/44 (2006.01) C12P 7/62 (2006.01)

Patent

CA 2490570

The invention relates to novel compounds, called serpentemycins, of formula (I), in which Y, R, R2, R3, R4, X, X2, X3, n, m and o are defined as per the description, said compounds being formed from the microorganism <i>Actinomycetales</i> sp. DSM 14865 during zymolysis. The invention also relates to chemical derivatives of the serpentemycins, to a method for their production and to the use of said compounds as medicaments, in particular for the treatment and prophylaxis of bacterial, infectious diseases.

La présente invention concerne de nouveaux composés appelés Serpentemycine, de formule (I), dans laquelle Y, R, R¿2?, R¿3?, R¿4?, X, X¿2?, X¿3?, n, m et o ont les significations données, qui sont formés à partir du micro-organisme Actinomycetales sp. DSM 14865, lors de la fermentation. La présente invention concerne également des dérivés chimiques de Serpentemycine, un procédé pour produire ce composé et son utilisation en tant que médicament, notamment pour traiter et prévenir des maladies infectieuses bactériennes.

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